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The cells were incubated with azide-PA at a final concentration of 100 M for 24 h and then fixed for measurements

Systemic Autoimmune Conditions: By targeting NF-B a pathway implicated in rheumatoid arthritis, lupus, and other autoimmune diseases KPV is being explored in models of systemic immune dysregulation

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These findings suggest that local vitamin D metabolism occurs within the brain, supporting region-specific actions

Notably, secondary and exploratory analyses show a promising signal for slowing eGFR decline and reducing risk of progression to kidney failure