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Berberine significantly inhibits the increase of Verrucomicrobia at the phylum level, inhibits Akkermansia at the genus level, and elevates the levels of SCFA-producing bacteria ( Lachnospiraceae ) ( Lactobacillus and Dubosiella , and an increase in abundance of undesirable bacteria Bacteroides , Escherichia, Shigella , and Akkermansia
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Sibley, C
Lactobacillus strains have been widely demonstrated to metabolize tryptophan into its derivatives, such as indole-3-aldehyde (IAld), indole-3-lactic acid (ILA), and indole-3-acetic acid (IAA) 64,68,69
Thomson D, Turner A, Lauder S, Gigler ME, Berk L, Singh AB, et al