Beyond deacetylation: the non-deacetylase functions of HDACs In addition to the protein deacetylation for HDACs, there are also several evidences showing that HDACs possess deacetylase-independent functions such as sumoylation, decrotonylation, ubiquitin-dependent function and lactylation eraser as shown below
Differential effects of bFGF and IGF-I on matrix metabolism in calf and adult bovine cartilage explants
The answer lies in a concept we prioritize above all else: bioavailability
[DOI: 10.1177/106002809502901213] [DOI] [PubMed] [Google Scholar] 52.Rahman I, MacNee W
Accuracy of the radioactive copper incorporation test in the diagnosis of Wilson disease
Examples include protein-based nanoparticles made from whey protein isolate (51, 52), zein (corn protein) (53, 54), or casein (55, 56), and polysaccharide-based systems using chitosan (57), alginate (58, 59), or pectin (60, 61)