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Inflammation in the central nervous system can further contribute to signaling changes and systemic insulin resistance

We explored trans-ethnic and multi-ancestry meta-analysis strategies

doi: 10.1016/j.gene.2022.146460 42 XuePZhuangHBaiTZengXDengJShaoSet al

Retatrutide has 2.5-times lower potency at the GLP-1 receptor than human GLP-1, 8.9-times higher potency at the GIP-receptor than human GIP and 2.9-times lower potency at the GCG-receptor than human GCG [42]

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