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The discovery that GHK-Cu binds directly to SIRT1 (Li et al., 2025) has generated particular interest, as SIRT1 is a central regulator of cellular longevity and stress resistance

Cardiovasc Intervent Radiol 28:578583 Lo CKL, Mertz D, Loeb M (2014) Newcastle-Ottawa Scale: comparing reviewers to authors assessments

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A clinical study found that oral glutathione supplementation significantly lightened facial skin, reduced dark spots, and improved overall skin appearance in middle-aged women after 12 weeks

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