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These patients may first present with ocular discomfort and photophobia and be found to have mild glomerular and/or tubular impairment

Recent findings have hinted that any abnormality in these two opposing processes can influence the quantity and quality of mitochondria, which will further affect mitochondrial function and the ability of cells to adjust their mitochondrial networks in response to physiological adaptations and stress conditions (Palikaras et al., 2015

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M.et al (2021)

IRP2 has also been shown to sense Fe-S cluster levels regardless of its degradation 138 , through a yet-unclear mechanism

However, the molecular mechanisms of this process mediated by neutrophils still remain elusive