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The iron-regulatory hormone hepcidin: a possible therapeutic target

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Both drugs show the prolonged circulation half-life and tumor bioavailability with developed approach

For background, this means that a drug company "has taken exhaustive measures to get it approved, so they've done all this testing and paid all this money," Decotiis explains

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The structure showed the FERM domain has a canonical three-lobe structure (F1F3), and the SH2 has a preserved SH2-like structure despite lacking the highly conserved arginine residue in the phosphotyrosine binding site (71, 72)