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The most commonly reported adverse events include: Nausea Vomiting Diarrhea Constipation These are generally dose-dependent and most pronounced during the dose escalation phase

61 Mahul-MellierA.-L.BurtscherJ.MaharjanN.WeerensL.CroisierM.KuttlerF.et al (2020)

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So I think its an interesting study, but (it) really portends us to really think about what our next steps are so we can get into more adjuvant approaches, in addition to this, at the same time, he added.