In essence, glutathione acts as a cellular bodyguard, protecting your cells from damage and ensuring they function optimally
114,115,116 Additionally, NADH or FADH 2 is the electron carrier for the mitochondrial membrane proteins, such as GPDM and FQR, and the metabolic enzymes in matrix, such as OGDH and PDH, all of which contribute to ROS production
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Post-mortem analysis of the prefrontal cortex showed significantly increased levels of 8-OH-Gua (see also above) which may in turn affect the aggregation of proteins (Balmus et al
For these reasons, topical glutathione is the safest option and the one we focus on here
Our findings, mirror the differences of Stage 2 or Stage 3 siblings when independently measured and show dramatic and statistically significant reductions of GPx3 in the most severely affect children ( p = 2.47 10 8 , Paired t-test) again with non-overlapping 95% confidence intervals (95% CI Unaffected Stage 2/3 [1.7 ug/ml, 2.1 ug/ml], 95% CI Konzo Stage 2/3 [0.98 ug/ml, 1.3 ug/ml]) (Fig