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Over the past few years, medications like Ozempic and Mounjaro have revolutionized the treatment of Type 2 diabetes and obesity and theyve soared in popularity as a result

doi: 10.1016/j.dci.2023.105093 43 Pineda-PampliegaJHerrera-DueasAMulderEAguirreJIHfleUVerhulstS

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The FDA recently said Eli Lilly s tirzepatide (marketed as Zepbound and Mounjaro) is no longer in shortage, meaning companies that sell compounded tirzepatide will soon have to take their products off the market

While EGFR family members can compensate IGF-IR inhibition and confer resistance to IGF-IR-targeted agents, IGF-IR can confer resistance to EGFR/ErbB2/ErbB3-targeted therapies as well