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In 2024, the FDA expanded the label to include reducing the risk of major cardiovascular events in adults with established cardiovascular disease and overweight or obesity based on the SELECT trial, which randomized 17,604 patients and showed a 20% reduction in major adverse cardiovascular events over a mean 40 months

Katie Tuttle Editor Katie Tuttle is an editor and writer specializing in food, nutrition, and product testing

These could signal a need for dose adjustment, a slower titration schedule, or evaluation for other underlying conditions

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These maintain the results and can be taken regularly to enhance the effects of injections

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