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Do not exceed the recommended dosage unless advised by a medical professional

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Australian surveillance data warn that 1,4-BD combined with alcohol may create delayed toxicity, because alcohol can temporarily slow the conversion of 1,4-BD to GHB, leading people to think the dose is weak and re-dose, only to experience a dangerous CNS depressant effect later

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10.1016/j.freeradbiomed.2020.09.005 13