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More serious but rare side effects include: Pancreatitis (inflammation of the pancreas) Gallbladder problems Changes in heart rate While these serious complications are uncommon, they underscore why these drugs require medical supervision

Lovejoy JC, et al

J Neurochem (2015) 135(2):3018

M., Reimann, F., & Blottire, H

And depending upon your vulnerability, you may end up in the emergency room with what's called acute kidney injury meaning your kidneys start, don't work very well at all

"If any appeal that we make is unsuccessful, there are other treatments that we can use," he says for example drugs like Contrave or a cheaper combination of generic naltrexone and bupropion