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A common cycling pattern is 4 weeks on, 4 weeks off to prevent tachyphylaxis, though continuous daily use has been studied in clinical trials for up to 14 days with good tolerability [2]

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doi:10.1093/ajcn/nqy185

Selank, a Peptide Analog of Tuftsin, Attenuates Aversive Signs of Morphine Withdrawal in Rats