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Brodsky SV (2014) Anticoagulants and acute kidney injury: clinical and pathology considerations

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This regeneration of cytosolic NAD + is a critical rate-sustaining step, as it replenishes the electron acceptor pool required for the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) reaction, thereby maintaining continuous glycolytic flux and rapid ATP production [13]

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Here, we report that dual blockade can also prevent muscle loss associated with glucagon-like peptide-1 receptor agonists and even increase muscle mass in both obese mice and non-human primates