It was found that pregnant mice exposed to APAP showed signs of liver toxicity, affected immune adaptation to pregnancy, harm to placental functional regions, decreased maternal progesterone, hindered fetal development, lower fetal weight, and decreased T-cell development
Its role is to transport long-chain fatty acids into the mitochondria, where they can be used to produce energy
The mice werent heavier
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In addition, these metabolic effects do not appear to be related to their diuretic action or intended pharmacological targets, raising concerns about the long-term metabolic impact of specific diuretics, particularly in vulnerable populations, including those with metabolic syndrome
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