(PubMed) Fan L, Feng Y, Chen GC, Qin LQ, Fu CL, Chen LH
showed that Tanshinone IIA (Tan IIA) mitigates silica-induced oxidative damage by enhancing Nrf2-dependent antioxidant defenses, significantly inhibiting fibrotic matrix deposition in experimental silicosis through the modulation of EMT dynamics and TGF-1/Smad3 transduction cascades ( 4 Integrating TCM with nanotechnology to inhibit ferroptosis in PF Notably, the chronic systemic administration of conventional anti-fibrotic therapies often leads to issues such as low solubility, poor stability, rapid clearance, and dose-limiting side effects (Wan et al., 2023)
Bar Beauty Medical, 46 Fort York Blvd, Toronto.
I would love to be able to test that
Its clinical translation will require formal validation in human studies and the development of advanced delivery systems to overcome restrictions in bioavailability
NAC, N-Acetyl Cysteine