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Short nights raise ghrelin and blunt the satiety hormones the entire protocol is built around, so a poorly slept week can blunt the appetite suppression you paid for

10.1111/j.1471-4159.2007.04770.x J

Given these anti-inflammatory effects, there is speculation that GLP-1 medicines could impair host immune defenses

In adulthood, GH treatment has been shown to have beneficial effects on lean and fat mass, muscle performance, and quality of life (116)

GLP-1 and GIP help reduce appetite and improve blood sugar

These include nerve damage, as well as eye, kidney, or heart disease, some of which may require hospitalization