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Protein deficiency in SAM disrupts many pathways in energy metabolism including the Tricarboxylic Acid Cycle, the Electron Transport Chain, and -oxidation and perturbs gut microbiota, iron and amino acid metabolism [135, 136]

Author contributions XT: Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing original draft, Writing review & editing

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PMID: 31178679

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