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[link] De Meyer SE, Briscoe L, Martnez-Hidalgo P, Agapakis CM, Estrada de-los Santos P, Seshadri R, Reeve W, Weinstock G, O'Hara G, Howieson J, Hirsch AM., "Symbiotic Burkholderia species show diverse arrangements of nif/fix and nod genes, and lack typical high affinity cytochrome cbb3 oxidase genes", Mol

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Abnormal accumulation of fluidedema, ascites, pleural effusioncan markedly increase the volume of distribution of drugs such as gentamicin that are hydrophilic and have small volumes of distribution