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In contrast, in normal non-cancer rectal tissue, metformin significantly altered the secretion of only three IL-17 related cytokines, suggesting that metformin differentially alters the inflammatory secretome of normal rectal tissue, when compared to rectal cancer tissue, which may support its potential utility as a radiosensitiser

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Meanwhile, Tesamorelin takes a focused approach, targeting stubborn abdominal fat and offering hope to those battling HIV-associated lipodystrophy

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