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In certain conditions, vitamin b12 drops to such low levels which can cause different diseases in your cats body and reason is impaired absorption of cobalamin

Taking 2 milligrams or less a day of vitamin B12 in supplements is unlikely to cause any harm.

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Researchers determine the specific conditions of each experiment, including peptide concentrations, exposure times, and study protocols, based on their research goals and institutional guidelines

Nature Communications (2018) 2