When the body takes a large oxidative hit, active glutathione is depleted, and the result is widespread oxidative damage
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[8] [9] In healthy cells and tissue, more than 90% of the total glutathione pool is in the reduced form (GSH), with the remainder in the disulfide form (GSSG)
GSTZ1 expression and chloride concentrations modulate sensitivity of cancer cells to dichloroacetate