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Currently, RM-718 is being tested in a four-part phase I clinical trial in participants with general obesity, HO, and Prader-Willi Syndrome (NCT06239116)

A systematic review of over 94,000 adults seeking obesity treatment found that 14% had binge eating disorder on clinical interview and up to 26% reported moderate-to-severe binge eating on self-report measures ( Melville et al., Int J Eating Disorders, 2025 )

Focus on gradual, sustainable weight loss through a combination of healthy eating and regular exercise

Invest Ophthalmol Vis Sci 2005

These include low platelet production in the bone marrow, increased platelet breakdown in the circulation, and increased platelet breakdown in the spleen or liver

One of the hallmarks of this disease is the hepatic hyperproduction of glucose through gluconeogenesis [87]