Because the half-life is 20-30 hours, one injection per day produces relatively stable receptor coverage
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More common with intramuscular administration than subcutaneous
Skin is thin there and it is less resilient to damage from swelling (allergies, puffiness) 2
Elevated MMA levels (greater or equal to 0.4 mcmol/L) may be a more reliable indicator of B12 status, because it indicates metabolic changes more specific to B12 deficiency.4 Norris recommends MMA and serum vitamin B12 tests for vegans, adding, You dont need to get tested just because youre vegan
Many practitioners recommend supplementing with oral methylcobalamin or sublingual B12 in addition to the compound, particularly for patients who have been on therapy for more than six months or who have documented low B12 levels