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This Review focuses on aberrant metabolism in the pathogenesis of OA, summarizing the current state of knowledge on the role of impaired metabolism in the cells of the osteoarthritic joint

As patients experience changes in body composition, ensuring adequate nutrient intake and maintaining lean body mass become essential for sustaining long-term outcomes

In MCAS, mast cells become overly reactive and release mediators like histamine, prostaglandins, and cytokines inappropriately

Our comparison of retatrutide versus tirzepatide explores the potential advantages

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Also, the produced kynurenines influence glutamate receptors and its consequent excitotoxicity