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Currently, more than 15 anti-cancer nanomedicines, including lipid-based NPs, protein-drug conjugates, and metallic NPs, have been granted approval status by the U.S

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Int J Cancer 97(6):740745 Kroning R, Lichtenstein AK, Nagami GT (2000) Sulfur-containing amino acids decrease cisplatin cytotoxicity and uptake in renal tubule epithelial cell lines

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Your metabolic rate decreases because you are now a smaller person requiring fewer calories