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Basic fibroblast growth factor improves trabecular bone connectivity and bone strength in the lumbar vertebral body of osteopenic rats

FDA approval for weight management occurred on April 1, 2026, with a type 2 diabetes indication anticipated in the second half of 2026

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These risks and uncertainties include, but are not limited to, Risk Factors identified in our filings with the Securities and Exchange Commission, including, but not limited to, our most recently filed Annual Report on Form 10-K, Quarterly Reports on Form 10-Q, and any amendments thereto

Nonetheless, these transient interactions are clearly essential for receptor activation, with mutation of the majority of residues within the TMD cavity decreasing exendin-P5 efficacy, but not affinity