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Long-standing active disease increases the risk of colorectal cancer, and severe cases can lead to life-threatening complications, including toxic megacolon and intestinal perforation (Rubin et al., 2025)

This overlap is part of why NAD+ support draws interest in the first place, since heavy alcohol use is associated with lower cellular NAD+ availability

Gently dab it on the spot, do not rub hard

[] Heavy metals may be found in the environment naturally and may also be introduced because of human activity

Store vials in the main compartment rather than the door, where temperature fluctuations occur more frequently