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It is a systemic metabolic disease, closely linked to obesity, type 2 diabetes, cardiovascular disease, and chronic kidney disease

Transition Patients to FDA-Approved Products: Health care providers should begin transitioning patients to the FDA-approved Mounjaro or Zepbound

Not dramatically, not all at once, but slowly

Primer sequences and gene characteristics are detailed in Table S1 of the supplementary data, with primers designed as previously described [30]