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Investigations focus on cell health proxies rather than clinical outcomes

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It is one of the best-known short peptide references in discussions around gastric peptide biology, tissue-signalling models, nitric-oxide pathways, and extracellular matrix research

This is mechanistically distinct from the appetite effect and explains why tirzepatide produces greater fat-mass loss relative to lean-mass loss compared to GLP-1 monotherapy in DEXA substudy data from SURPASS-3 [24]

However, prolonged or excessive inflammation can slow down recovery and make it more difficult