K., Liu, B., & Cui, X
Introduction The technology of semen cryopreservation effectively promotes the application of technologies including genetic resource conservation, zootechnical management, and artificial insemination ( However, the cold shock and alterations in atmospheric oxygen seriously led to biochemical, biophysical, ultrastructural, molecular, and functional alterations ( To ameliorate oxidative stress-related damage, the supplementations of antioxidants, including vitamins, coenzymes, exosomes, liposomes, nanomaterials and trace elements such as selenium (Se), copper, and zinc to semen extender have been widely conducted (29)
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However the down side to this increased mitochondrial function was that more oxidative damage occurred (3) , so the researchers decided to add the powerful mitochondrial antioxidant alpha lipoic acid (ALA) to the mix to see if they could get the best of both worlds: increased mitochondrial energy output, with reduced mitochondrial damage
A prespecified SELECT analysis reported that semaglutides cardioprotective effects were independent of baseline adiposity and weight loss, with only a small association with measures like waist circumference, again supporting more than weight loss mechanisms
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