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For instance, studies have indicated that intravenous (IV) glutathione administration can lead to significant improvements in liver function markers among patients with fatty liver disease
However, taking higher-than-recommended doses for long periods is not advised
Curcumin inhibits NF-kB and Wnt/-catenin pathways in cervical cancer cells
Holtz AG, Lowe TL, Aoki Y et al (2023) Asymmetric and symmetric protein arginine methylation in methionine-addicted human cancer cells
Polyunsaturated fatty acids increase lipid radical formation induced by oxidant stress in endothelial cells
At minimum: Outcomes Weight trend (weekly average) Waist circumference Body composition if available (DEXA, BIA with consistency) Strength markers (basic lifts, grip strength, functional tests) Safety Blood pressure + resting HR A1c and fasting glucose (more often if diabetes) CMP (liver/kidney) Lipids (periodic) If manipulating GH/IGF-1 signaling: IGF-1 (and clinical context matters) Stop criteria Persistent tachycardia, edema, severe fatigue, worsening glycemia, abnormal labs, or new symptoms you cant explain The what to ask your clinic questions (high signal, low fluff) If a clinic recommends a peptide stack, ask: What is the problem were solving, in one sentence
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