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GLP-1RAs significantly reduced endoplasmic reticulum (ER) stress-associated -cell death and recovered rat insulinoma cell line (INS-1) cells from ER stress-mediated translational repression in a PKA-dependent manner [34]

Franssen, C

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Pregnant women or those planning pregnancy require specialist advice, as nutritional needs differ and semaglutide must be discontinued at least 2 months before a planned pregnancy

December 22nd, 2025: JPML Assigns GLP-1 Vision Loss Cases to Judge Handling Stomach Injury MDL The Judicial Panel on Multidistrict Litigation has directed all federal lawsuits alleging vision loss linked to Ozempic, Wegovy, and other GLP-1 medications to be centralized in the Eastern District of Pennsylvania