Long-term skin damage and aging : Skin whitening tablets may provide instant cosmetic improvements, but their long-term effects might lead to premature skin aging and lasting damage
Research generally shows that Metformin leads to gradual and modest weight loss
Currently, two FDA-approved GLP-1 receptor agonists are directly derived from the Gila monster venom peptide exendin-4: exenatide (Byetta) and exenatide extended-release (Bydureon, Bydureon BCise)
Prolonged use of binders without proper timing and supplementation can lead to severe nutrient deficiencies, particularly of fat-soluble vitamins (A, D, E, and K), magnesium, zinc, and essential fatty acids, which are already often depleted in chronic illness patients
Some patients may regret treatment because they expected rapid weight loss, misunderstood its purpose, or were not prepared for regular injections and follow-up care
PLos ONE 6 6 , e21486 (2011)