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GLP-1 receptor agonists work by mimicking the action of endogenous GLP-1, a hormone that stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and promotes satiety through central nervous system pathways

Semaglutide GLP-1 functions by mimicking the actions of the GLP-1 hormone, which helps control blood sugar levels

The main ingredient, berberine, is found naturally in a range of plants and is thought to boost the release of GLP-1 , a hormone that already exists in the body

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However, these are not actual GLP-1 drug patches and there is no strong clinical evidence that transdermal patches with these herbal ingredients can increase the bodys natural GLP-1 levels 3