The E3 ligase acts as a docking platform to attach the Ub-containing E2 enzyme to a particular substrate, enabling the Ub to bind to the lysine residue of the substrate protein
Since it is a natural detoxifier, it improves the health of the body's cells to reverse ageing
Relationships between vitamin D, gut microbiome, and systemic autoimmunity
Plant Signal Behav 5:171175 Kim RH, Smith PD, Aleyasin H, Hayley S, Mount MP, Pownall S, Wakeham A, You-Ten AJ, Kalia SK, Horne P, Westaway D, Lozano AM, Anisman H, Park DS, Mak TW (2005) Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress
The honest answer is: it's more interesting than most peptides in this space, the mechanism is real, there's some legitimate clinical evidence and there are also significant gaps in the data that the internet tends to paper over
Astaxanthin supplementation can benefit eye health in a few different ways