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Because free-radical damage is in itself a major contributor the aging process, this age-related decrease in glutathione production can lead to a self-perpetuating cycle of mental and physical decline

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doi: 10.3389/fmed.2023.1124275 Received 14 December 2022 Accepted 27 February 2023 Published 22 March 2023 Volume 10 - 2023 Edited by Ana Sandoval-Rodriguez, University of Guadalajara, Mexico Reviewed by Angelo Armandi, University of Turin, Italy

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3rd Microsecond timescale backbone conformational dynamics in ubiquitin studied with NMR R1rho relaxation experiments

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