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T., & Ou, H
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A group of researchers, including oncologists and data scientists, from the University of Florida and Indiana University hypothesized that GLP-1s hold promise in oncology due to their ability to lower glucose, adiposity, insulin resistance, and systemic inflammation factors associated with cancer progression, according to a July 2025 paper published in JAMA
MOTS-c and NAD+ work differently but overlap in one key area: MOTS-c increases cellular NAD+ levels as part of its mechanism, which means stacking both compounds can create a synergistic effect rather than a redundant one