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While it is difficult to analyze methionine dependence for tumors in cancer patients, there have been a number of clinical trials that have studied the enzymes involved in methionine metabolism

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Additional benefits include potential for weight reduction, modest blood pressure lowering, and cardiovascular risk reduction in diabetic patients

a phase 2 trial published in the New England Journal of Medicine (Jastreboff et al., 2023) demonstrated significant weight reduction in adults with obesity, and further trials are ongoing (see ClinicalTrials.gov for current study identifiers)

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Support memory and concentration: Contributes to cognitive health and supports mental functions