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For complex lipidated peptides such as semaglutide and tirzepatide, molecular-mass confirmation alone may not fully characterize sequence-related or positional impurities, including partial sequence deletions, epimerization, incorrect acylation site, incomplete acylation, positional isomers, oxidation products, or aggregation-related species
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Its main role is to stimulate insulin secretion, which improves glucose levels and insulin tolerance, and as a result reduces hyperglycemia (high blood sugar)
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Corresponding horseradish peroxidase-conjugated secondary antibodies were purchased from Sigma (St
Retrieved August 24, 2019
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