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Because synthetic GLP-1 doesn't break down as easily as the real thing, it can "help create the feeling that you just ate dinner, so you don't want more food," according to Weill Cornell Medicine obesity expert Louis Aronne, MD, whose most recent research on the drugs appeared in the Journal of the American Medical Association in November 2024

The researchers compared rates of suicidal ideation or attempts for kids whod been prescribed GLP-1 drugs for obesity with those of children treated with a behavioral intervention, such as diet and exercise