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To produce an equivalent stimulation of PYY and equivalent satiety, obese individuals needed to consume a much greater caloric load than their lean counterparts.8688 However, not all studies have detected a difference in fasting PYY concentrations between lean and obese groups.89 Current data suggest that impaired postprandial PYY release may impair satiety and help to maintain obesity, if not act as a primary driver of initial development of obesity.90 The anorectic effects of GLP-1 are preserved in obesity

These findings suggest a potential role for osteocyte ferroptosis in age-related osteoporosis

Someone with severe abdominal swelling, significant pain, or repeated vomiting should seek medical guidance rather than simply adding more fiber and assuming the problem is routine constipation

The gastric-emptying effect often attenuates over time after dose stabilization

Which foods contain L-carnitine

Metformin is not recommended if the serum creatinine level is 1.4 mg/dl in females and 1.5 mg/dl in males due to the rare but fatal lactic acidosis risk