Some amount of all the antioxidant enzymes, which may protect spermatozoa from oxidative attack, are also made by the epididymis during storage
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Insulin-like growth factor-1 (IGF-1) has long been implicated in prostate cancer (PCa) pathogenesis and progression, promoting tumor growth through activation of the IGF-1 receptor (IGF-1R)
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No conventional receptor unique to DSIP has been confirmed, and no clearly established precursor gene explains its synthesis as a standalone neuropeptide
In addition, the released lactate can bind to the hydroxycarboxylic acid 1, HCA1 (encoded by the HCAR1 gene) receptor triggering autocrine effects in the adipocyte or paracrine effects in other cells