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The polygenic nature of breast cancer has been illuminated by the polygenic risk score computed based on multiple genome-wide association studies (GWAS), implicating over 180 single-nucleotide polymorphisms (64, 65)

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Targeting oncogenic serine/threonine-protein kinase BRAF in cancer cells inhibits angiogenesis and abrogates hypoxia

As noted in the literature when selecting these targets, reduced levels of IGF1 have been reported in children, adolescents and adults who are autoantibody positive (AAb+) or who have type 1 diabetes [36]

Therefore, future experimental models and human studies should explore in depth the specific mechanism of action of acupuncture on pathological changes in Tau and how this traditional medical technique can be effectively utilized to treat or prevent TBI-induced neurodegenerative diseases (Liu, 2023)