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The redox cycling enzymes thioredoxin, thioredoxin reductase, sulfiredoxin, peroxiredoxin, GSH peroxidase, superoxide dismutase 1, and catalase, and several GSH S-transferases, which are the enzymes mediating the elimination of ROS, are all Nrf2 targets (242)

However, a significant decrease in cell viability was observed when these compounds were used at 10,000 M, indicating their cytotoxic effect

Calorie restriction increases fatty acid synthesis and whole body fat oxidation rates

Glutathione is an antioxidant that may play an important role in detoxification processes in the body, particularly in the liver

Curcumin induces changes in expression of genes involved in cholesterol homeostasis

If left untreated, it can lead to Heart palpitations and shortness of breath Weakness, tiredness, or lightheadedness Pale skin Vision loss Constipation, diarrhea, loss of appetite, or gas A smooth tongue Depression Memory loss Behavioral changes Numbness or tingling Muscle weakness Problems walking not trying to give you the wobbles here!), low levels of B12 can be linked to the development of pernicious anemia, dementia, or osteoporosis