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J Toxicol Sci 33:389403

19 mg/kg) in cats (n = 6)

Elamipretide selectively accumulates within the inner mitochondrial membrane, where it exerts its cytoprotective effects

Bottom line: Morning doses act as a protective shield for the day ahead, while evening doses support the body's internal repair and detoxification work that happens during sleep

Release of Ca2+ from the endoplasmic reticulum and its subsequent influx into mitochondria trigger celastrol-induced paraptosis in cancer cells