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The discovery of parkin and UCH-L1 mutations, as well as their involvement in the ubiquitin-proteasomal system, ushered in a new age of research into changes in protein processing in dopaminergic cells via both proteasomes and lysosomes (Kumar et al., 2022)

Reconstituted solutions are generally advised to be stored at low temperature, shielded from light, and used within a defined experimental window to maintain potency and limit microbial risk, in accordance with local lab practices

doi: 10.1038/288715a0

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Intracellular Bioavailability: Effective detoxification requires GSH to enter the cell cytosol

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