Nausea, sulfur burps and fatigue can be unpleasant, but they're usually manageable
Almost three years
A population-based study of 467 matched pairs of GLP-1 users and non-users with type 2 diabetes and liver cirrhosis found GLP-1 use associated with lower risks of death, cardiovascular events, decompensated cirrhosis, hepatic encephalopathy, and liver failure
Bupropion is a dopamine and norepinephrine reuptake inhibitor that helps reduce appetite and can improve mood at the same time
The question has significant clinical importance given the widespread use of these medications and the serious nature of suicidal ideation
It was impressive to see that every dose of retatrutide resulted in clinically meaningful weight reduction for nearly all participants, and people with severe obesity on the highest dose lost an average of 30% of their body weight over two years, said Ania Jastreboff, the lead investigator of the study, in a press release