While the liver is the main site of VDBP synthesis and secretion [16,17], the conversion of 25(OH)VD to its active metabolite, 1,25(OH) 2 VD (calcitriol), is carried out by CYP27B1 in both renal and non-renal tissues [18] (Figure 1)
Molinaro et al., 2019)
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Imai, J
One exception is the The studies focused on two conditions that affect millions worldwide: age-related macular degeneration (AMD) and cataracts
CD14 is a protein present on the cell membrane that recognizes and binds LPS [40]